I agree with Jim McNamara that this is something you should have your DBA look at.
My first two guesses are:
1) Configuration error (for example, you need to adjust your init.ora parameters)
... and/or ...
2) Client configuration error
Talk to your DBA.
PS:
You haven't given us any clue as to what version of Oracle you're running, what your client environment is, whether or not you can connect to Oracle at all (e.g. through sqlplus), what other errors you might be seeing, and whether or not you have any trained Oracle support staff available.
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