As others have told you you DO just have to move the profile directory, but you also need to make sure that Thunderbird is told to use that new directory with the profiles.ini file.
Copy the "Thunderbird" directory from Windows (that contains a at least a dir called profiles and a file called profiles.ini) to her home directory and rename it ".thunderbird". Then open profiles.ini and make sure that you have the correct path to the profile directory (the gibberish.default dir) whether absolute or relative.
So long as you get everything right, it will work. If any little thing isn't quite right, Thunderbird will start a new profile from scratch. That can, however, be beneficial as it gives you a correct template for profiles.ini relative to the profile storage location which you can then check against to see why you haven't got it right.
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