Hi there onthos!
Welcome to LinuxQuestions.org. Well, I think it's better if you tell us what you've been trying to do and why exactly it does not work (error messages, crashes, etc).
Knowing your graphics card and the drivers you are using are always a plus.
Wine is a bit tough sometimes to get things working though. WineX (
www.transgaming.com) now known as Cedega, does wonder for Linux gamers. If you like games and if you love Linux (I surely love both), Cedega is a must.
Either way, a common problem with Diablo (and any other multi-CD's games) is when you've to swap disks during installation. If that's your problem, take a look in here:
http://www.linuxquestions.org/questi...476#post331476
Good luck mate!