I guess you have to configure wine. I have both used wine to run stuff from a installed win2000 and from scratch with absolutely nothing. To get it working just empty, well.... to do it in a organized fashion, create a ~/windows/ directory (I use it as the C
, create the necessary folders in it (~/windows/windows [C:\windows], ~/windowswindows/system, ~/windows/windows/system32, ... ) ... and edit the ~/.wine/config file to use it.
If you want to use it to run stuff you have installed in the windows you have running alongside with linux, then use the ~/.wine/config file to tell wine how your windows system is running (the most important thing is the partition types and letters.... though it's not the only detail to be careful about).
Either case it's not that difficult. Just read the documentation at /usr/share/doc/wine*.
there you can see how to do it.
PS.. Oh, one detail... if you are trying to access a NTFS partition, that could be the problem, cause (probably) it's mounted read-only... and so if the program wants to write just a little bit of anything, a exception is gonna raise. You could consider mounting it read-write..... but I think it's still in "experimental" development stage.. I might be wrong anyway. Good luck!