Are you the OP?
What is exactly the error you get?

I run the command and below are the output. Am I access the wrong path and run the command ?

root@infra:~# /path/to/clamd -V
-bash: /path/to/clamd: No such file or directory
root@infra:~# /path/to/clamsd -v
-bash: /path/to/clamsd: No such file or directory
root@infra:~# locate clamd
/usr/local/clam/bin/clamdscan
/usr/local/clam/sbin/clamd
/usr/local/clam/man/man1/clamdscan.1
/usr/local/clam/man/man8/clamd.8
/var/amavis/clamd
root@infra:~# cd /usr/local/clam/bin
root@infra:/usr/local/clam/bin# cd clamdscan
-bash: cd: clamdscan: Not a directory
root@infra:/usr/local/clam/bin# ls
clamav-config* clamdscan* clamscan* freshclam* sigtool*
root@infra:/usr/local/clam/bin# clamd -V
-bash: clamd: command not found
root@infra:/usr/local/clam/bin# clamdscan -V
-bash: clamdscan: command not found
root@infra:/usr/local/clam/bin# cd..
-bash: cd..: command not found
root@infra:/usr/local/clam/bin# cd ..
root@infra:/usr/local/clam# cd sbin
root@infra:/usr/local/clam/sbin# ls
clamd*
root@infra:/usr/local/clam/sbin# clamd -V
-bash: clamd: command not found
root@infra:/usr/local/clam/sbin# clamdscan -V
-bash: clamdscan: command not found
root@infra:/usr/local/clam/sbin#

I run the command and below are the output. Am I access the wrong path and run the command ? It does not show me any version also.

root@infra:~# /path/to/clamd -V
-bash: /path/to/clamd: No such file or directory
root@infra:~# /path/to/clamsd -v
-bash: /path/to/clamsd: No such file or directory
root@infra:~# locate clamd
/usr/local/clam/bin/clamdscan
/usr/local/clam/sbin/clamd
/usr/local/clam/man/man1/clamdscan.1
/usr/local/clam/man/man8/clamd.8
/var/amavis/clamd
root@infra:~# cd /usr/local/clam/bin
root@infra:/usr/local/clam/bin# cd clamdscan
-bash: cd: clamdscan: Not a directory
root@infra:/usr/local/clam/bin# ls
clamav-config* clamdscan* clamscan* freshclam* sigtool*
root@infra:/usr/local/clam/bin# clamd -V
-bash: clamd: command not found
root@infra:/usr/local/clam/bin# clamdscan -V
-bash: clamdscan: command not found
root@infra:/usr/local/clam/bin# cd..
-bash: cd..: command not found
root@infra:/usr/local/clam/bin# cd ..
root@infra:/usr/local/clam# cd sbin
root@infra:/usr/local/clam/sbin# ls
clamd*
root@infra:/usr/local/clam/sbin# clamd -V
-bash: clamd: command not found
root@infra:/usr/local/clam/sbin# clamdscan -V
-bash: clamdscan: command not found
root@infra:/usr/local/clam/sbin#

When I told you to run /path/to/clamd, I meant to replace /path/to with the actual path to the command. Anyway the correct command is:
If you want to run the command from inside the /usr/local/clam/sbin directory then you should run:

Thanks..
I have run the command and the version that i'm using now is ClamAv version 0.75.

That's a pretty old version, so it's pretty normal it cannot update the virus definitions. You can check if that's the case running freshclam manually:
and see if it reports any errors.

You are definitely right. I need to update clamav and my current functionality level is 2.

root@infra:/usr/local/clam/bin# ./freshclam
ClamAV update process started at Tue Sep 11 15:21:04 2007
Reading CVD header (main.cvd): OK
main.cvd is up to date (version: 44, sigs: 133163, f-level: 20, builder: sven)
WARNING: Your ClamAV installation is OUTDATED - please update immediately !
WARNING: Current functionality level = 2, required = 20
Reading CVD header (daily.cvd): OK
Downloading daily.cvd[*]
daily.cvd updated (version: 4238, sigs: 18870, f-level: 21, builder: ccordes)
WARNING: Your ClamAV installation is OUTDATED - please update immediately !
WARNING: Current functionality level = 2, required = 21
Database updated (152033 signatures) from database.clamav.net (58.221.222.69).

Thanks.