I think that generally the answer is yes. Some applications won't run multiple instances. During startup they check to see if there is another instance running. If they find one they will exit. Otherwise you can run multiple instances of almost anything from web browsers to database servers.
Where is the information? Since this functionality is generally available there isn't one place to discuss running multiple instances of software in general. For example, where would you find information for running multiple instances of Acrobat Reader? The answer is nowhere. The software just allows multiple instances. There isn't any information about how to run multiple instances because you just start the second, third, instance.
I have to infer from your question that you are having trouble running multiple instances of a particular software application. More information about the details of your situation would be helpful.
I think that the first place to look when you have questions about a specific application is the technical support for that sofware. That may be available on the web or by telephone.