Nope, acpi works just fine but you may need to build a custom kernel;
Code:
$ uname -a
Linux Aspire5000 2.6.19-rc4 #1 Tue Oct 31 08:36:37 EST 2006 x86_64 x86_64 x86_64 GNU/Linux
$ cat /etc/*release
Red Hat Enterprise Linux ES release 4 (Nahant Update 4)
$ cat /proc/interrupts
CPU0
0: 20726033 IO-APIC-edge timer
1: 28227 IO-APIC-edge i8042
8: 0 IO-APIC-edge rtc
11: 236544 IO-APIC-fasteoi acpi
12: 4646650 IO-APIC-edge i8042
14: 76160 IO-APIC-edge ide0
15: 736303 IO-APIC-edge ide1
17: 296592 IO-APIC-fasteoi wlan0
18: 5464 IO-APIC-fasteoi SiS SI7012, SiS SI7013 Modem
19: 1 IO-APIC-fasteoi yenta
20: 0 IO-APIC-fasteoi ohci_hcd:usb1
21: 0 IO-APIC-fasteoi ohci_hcd:usb2
23: 0 IO-APIC-fasteoi ehci_hcd:usb3
NMI: 37904
LOC: 20726867
ERR: 0
Don't let /etc/*release output fool you, I installed the redhat-release rpm from RHEL4 for update compatibility reasons I'm really running RHEL5Beta1 (updated) which is based on FC6.