Sorry about the delay, I forgot to check my mail..
well, let's go step by step.
1) did you install the winetool AND the wine versions recomended in the winetools website? (in the winetools download page is a link to old versions of wine).
So, first of all: get the recommended wine & winetools.
-now I'll suppose you've got such apps installed and working ok-
2) I know a couple of ways to try install a windows binary. first: use the command-line to go thru your path till get the cdrom; once there you should be able to see the windows installer, lets figure it name is 'install.exe'. then, in the comand-line type: wine installer.exe
that should trigger the windows installer. If everything is ok, the windows installer for your app would install it, in exactly the same way it do under a windows partition.
3) the other way to install it is thru the winetool's GUI (you call it typing "wt2" in the command-line). In the main menu, click in "install tested software" -or something similar--mine is the spanish-version of winetools.
Yes-yes..I know: your app is not listed in the tested software list, but here's the trick:
once in such list, click in the office menu to display all of it choices, and click "microsoft office 2000". When it ask if you wanna use the default, you choice 'NO', so it'll prompt you to select the file by hand in a file-system tree, and now is when you look for your cdrom, find the installer and select it. -since now, and if everithing is ok, the install process is the same than in windows.
* about your cdrom path: I cannot help you with that cause I have a different distro, so I'm not familiar with yours. If winetools complains that it can't find the cdrom, there's no problem of winetools by itself, but your distro paths (maybe winetools is searching the cdrom in a sort of 'default cdrom path', but fedora maybe use another path for the cdrom) In this case, I recomend you to ask for help in your distro forum.
** I've installed macromedia fireworks using wine, with no problem at all, so I guess you should be able to install dreamweaver as well.
hope this help you.