You want to know if a current distro with 2.6 kernel supports USB, VGA, keyboard and mouse?
If so, yes it does. It however does not imply that your hardware (printer, scanner etc) will work immediately; you might have to do some research on the internet to figure out how to get it working (and maybe download an update of some software or some additinal software). And if you acquire hardware that is newer than the distro, it might not be supported and it might take a while before it is supported. In which case you can always try to write your own driver