out of the box ... well I think fedora is pretty great! just install it and start apache and it's all good, if ur looking for a gui into setting up your apache server webmin is a great program, well worth a look
http://fedora.rehat.com
http://www.webmin.com
check out the how-to's on my website there is a lot of information on setting up webservers there, just search for apache
hope this helped