I just got a ASUS all in one that came w windows 10, which proved to be the work of a fiend. Dell and HP seem to know which of their products will run linux, not ASUS Anyone ever tried Ubuntu linux on ASUS desktop?

Depends on the exact model, I guess.

It might help to post the make/model and the specs, although, if it will run Windows 10, it will likely run just about any Linux.

A search for replace Windows 10 with Linux will turn up a number of howto articles and tutorials.

Put any live linux to the USB stick (with Unetbootin or Rufus), disable secure boot in BIOS and boot into live USB system. And you can see, does your desktop linux compatible or not.

As an initial simple&quick temporary alternative to install, maybe VirtualBox.org
Web-research of course. Welcome to LQ!!!

As Teufel mentioned best test. There are websites that list compatibility too. I don't know of any Asus that won't run Linux, you just won't get tech support from them for a Linux install (sort of, I got a little support for mine because it came with no O/S installed but really had to pry out of them as it was clearly a hardware problem although I no longer recall the exact problem). I've been running Linux on an Asus desktop pc with M5A88-M mobo for 5+ years and love it. The M5A97's and 78's and 99's and the gaming ones all will run Linux. M5A88-M is outdated a few years now. Laptops seem to be more problematic from what I see in the forums.

Maybe it will help.
I am using an ASUS ZenBook UX305 laptop with Fedora since several years without any major hardware problem.
The only one I remember seemed to be linked to poor made power supply cables that somehow prevented the wifi card to be seen by the kernel and ultimately to work.

I do have an old Asus Motherboard which has a Pentium CPU, it works fine with ElementaryOS.

Asus is the most open-source-resistant company I've ever seen! It refuses to cooperate except under the greatest pressure, and then only for a moment, with one particular product, and then it's back to square one with Asus.

But most of their stuff will just work with Linux.

If one of those touch screen only, face recognition Windows 10 models.

I'd hook a external keyboard and mouse and have at it. Use a 4.xxx kernel . It should be a I7 computer. If so. I'd run linux on it and put Windows 10 in Virtual box. If possible. Another way is to run Linux off a usb 3 capable pendrive installation with persistence. I bet it would scream run with that setup.

PS. I run touchscreen keyboards and mouse gestures on older Touchscreen gear. Linux has that covered mostly also. But I am not sure with something so new.

Do you have any links for this? Just interested as I have some ASUS hardware.

Thanks