^ that was my first thought, too, but the accepted answer is a little confusing i think.
johnnyreb:
be sure wine is not running.
create a directory (let's say we call it 'wine') on that larger hd.
copy all the contents of ~/.wine into that directory.
create a symbolic link:
Code:
ln -s /that/larger/hd/wine ~/.wine
=> instant gratification!
(however, you should now make sure the hd is mounted before starting wine)
