I discovered the Nix package management system recently (cross platform)
www.nixos.org/nix
Assuming space isn't an issue, and you don't have root access, it seems appealing.
Has anyone had experience using it in a company?
For example, whilst the build design is very well thought out, they state that haven't thought much about runtime design. I found it appears to build everything with RPATH (not RUNPATH), which would preclude you from using LD_LIBRARY_PATH if you needed to fix something.
I've also briefly looked at Gentoo Prefix. What does Nix solve which Prefix doesn't?