To Blacklist Modules in embedded device

Hello Everyone,
I am working on Embedded device of linux, basically i want to disable USB on it, however i had tried modprobe, it's not working, and i had also done echo disable > /power/wakeup , at the end it's not working when i reboot my system, i have no file named /etc/modprobe.d/blacklist.conf , and m not able to create that one even. so please help me at this front, thanks in advance

USB support might be compiled in the kernel. You could re-build the kernel to disable it or build USB support as modules that you can load / unload as you need.