I have an old Asus EEE which had EasyPeasy installed, and I wanted a regular Ubuntu Remix on it, so it was time for a reinstall. Since it was definitely not a "server", I tried smeezekitty's suggestion, just a bit curious...
Well it complained about /var/lock and /var/run being busy, so I had to use a live cd to get rid of it all.
It did boot afterwards - but just hanged with a black screen. I guess no service could start, but I didn't feel like diagnosing or fixing the "problem", so I just did the reinstall.
Years ago, I deleted /etc. It had a similar effect but the error messages was much more fun.