Hello,

I've seen this around and I've tried to work through it, but I can't figure out why I get an IRQ nobody cares message.

Everything works fine until I launch molecular modeling programs which use the GPL such as VMD, PyMol or Swiss-PDB then I get an IRQ interupt.

The interrupt occurs on IRQ 16 which is my eth0 device. # cat /proc/interrupts

CPU0
0: 266014 IO-APIC-edge timer
2: 0 XT-PIC cascade
8: 1 IO-APIC-edge rtc
11: 0 IO-APIC-edge i915@pci:0000:00:02.0
14: 2084 IO-APIC-edge ide0
16: 3739 IO-APIC-level eth0
18: 0 IO-APIC-level uhci_hcd
20: 13829 IO-APIC-level libata
21: 7576 IO-APIC-level uhci_hcd, ehci_hcd
22: 0 IO-APIC-level uhci_hcd
23: 0 IO-APIC-level uhci_hcd, Intel ICH6
NMI: 0
LOC: 266017
ERR: 0
MIS: 0

How can I fix this?

Thanks in advance for any help, Josh

In case anyone has any helpful pointers, here is the tail of dmesg after initializing one of the graphic rendering programs:

irq 16: nobody cared!
[<c0103c8e>] dump_stack+0x1e/0x20
[<c019117b>] __report_bad_irq+0x2b/0x90
[<c01912a0>] note_interrupt+0x90/0xb0
[<c0190d55>] __do_IRQ+0x105/0x110
[<c010519c>] do_IRQ+0x1c/0x30
[<c0103822>] common_interrupt+0x1a/0x20
[<c01010f4>] cpu_idle+0x44/0x60
[<c03ec89d>] start_kernel+0x16d/0x1b0
[<c010019f>] 0xc010019f
handlers:
[<e0885400>] (tg3_interrupt+0x0/0x150 [tg3])
Disabling IRQ #16


I also meant that these programs use GL for graphics, not GPL.

also 'lspci -v' shows that 'IDE interface: Intel Corporation82801FB/FW (ICH6/ICH6W) SATA Controller ' is on IRQ 16, something not reported in /proc/interrupts

Solved.

Because everything is hard-wired to the mother board I couldn't try switching PCI slots.

Many posts suggested PNP in the bios, but I am stuck with Dell.

Here my only options were to either get a new bios chip or compile a kernel without PNP.

The kernel worked.