I am unable to cause the 'mail' command to send mail from my linux ubuntu 15.10 computer. File 'mail.log' typically reports "Connection timed out".

Specifically, the log reports:
Jan 5 12:29:53 pegasus postfix/smtp[9006]: connect to mx01.gmx.com[74.208.5.27]:25: Connection timed out
Jan 5 12:30:23 pegasus postfix/smtp[9006]: connect to mx00.gmx.com[74.208.5.4]:25: Connection timed out

I suspect that my ISP (verizon) is blocking port 25 and thus causing the problem: however, I have been unsuccessful in trying to change the smtp port to either 465 (as Verizon recommends) or 587 (as others recommend). Following is my master.cf file:

smtp inet n - - - - smtpd
465 inet n - - - - smtpd
#smtp inet n - - - 1 postscreen
#smtpd pass - - - - - smtpd
#dnsblog unix - - - - 0 dnsblog
#tlsproxy unix - - - - 0 tlsproxy
#submission inet n - - - - smtpd
# -o syslog_name=postfix/submission
# -o smtpd_tls_security_level=encrypt
# -o smtpd_sasl_auth_enable=yes
# -o smtpd_reject_unlisted_recipient=no
# -o smtpd_client_restrictions=$mua_client_restrictions
# -o smtpd_helo_restrictions=$mua_helo_restrictions
# -o smtpd_sender_restrictions=$mua_sender_restrictions
# -o smtpd_recipient_restrictions=
# -o smtpd_relay_restrictions=permit_sasl_authenticated,reject
# -o milter_macro_daemon_name=ORIGINATING
#smtps inet n - - - - smtpd
# -o syslog_name=postfix/smtps
# -o smtpd_tls_wrappermode=yes
# -o smtpd_sasl_auth_enable=yes
# -o smtpd_reject_unlisted_recipient=no
# -o smtpd_client_restrictions=$mua_client_restrictions
# -o smtpd_helo_restrictions=$mua_helo_restrictions
# -o smtpd_sender_restrictions=$mua_sender_restrictions
# -o smtpd_recipient_restrictions=
# -o smtpd_relay_restrictions=permit_sasl_authenticated,reject
# -o milter_macro_daemon_name=ORIGINATING
#628 inet n - - - - qmqpd
pickup unix n - - 60 1 pickup
cleanup unix n - - - 0 cleanup
qmgr unix n - n 300 1 qmgr
#qmgr unix n - n 300 1 oqmgr
tlsmgr unix - - - 1000? 1 tlsmgr
rewrite unix - - - - - trivial-rewrite
bounce unix - - - - 0 bounce
defer unix - - - - 0 bounce
trace unix - - - - 0 bounce
verify unix - - - - 1 verify
flush unix n - - 1000? 0 flush
proxymap unix - - n - - proxymap
proxywrite unix - - n - 1 proxymap
smtp unix - - - - - smtp
relay unix - - - - - smtp
# -o smtp_helo_timeout=5 -o smtp_connect_timeout=5
showq unix n - - - - showq
error unix - - - - - error
retry unix - - - - - error
discard unix - - - - - discard
local unix - n n - - local
virtual unix - n n - - virtual
lmtp unix - - - - - lmtp
anvil unix - - - - 1 anvil
scache unix - - - - 1 scache
#
uucp unix - n n - - pipe
flags=Fqhu user=uucp argv=uux -r -n -z -a$sender - $nexthop!rmail ($recipient)
#
# Other external delivery methods.
#
ifmail unix - n n - - pipe
flags=F user=ftn argv=/usr/lib/ifmail/ifmail -r $nexthop ($recipient)
bsmtp unix - n n - - pipe
flags=Fq. user=bsmtp argv=/usr/lib/bsmtp/bsmtp -t$nexthop -f$sender $recipient
scalemail-backend unix - n n - 2 pipe
flags=R user=scalemail argv=/usr/lib/scalemail/bin/scalemail-store ${nexthop} ${user} ${extension}
mailman unix - n n - - pipe
flags=FR user=list argv=/usr/lib/mailman/bin/postfix-to-mailman.py
${nexthop} ${user}

Are you doing direct-to-MX or smart-host through smtp.verizon.net?

I really don't understand your question. I just issue the command: 'mail -s "my subject" recipient@domain.com < filename', where 'filename' is a file containing my message.

As far as I know, I'm using smtp.verizon.net
My main.cf file contains the line;
relayhost = [smtp.verizon.net]:465