For one, that's nearly impossible to read. Try using the code tag next time.
Secondly, tuning your database server is entirely dependent on the application(s) running on the server. For example, if your application does not have a lot of records in each table, having large key buffers does not benefit you much.
Have you read the documentation linked from the MySQL forums:
http://forums.mysql.com/read.php?24,92131,92131 ?