If you want to block packets either that will be forwarded OR that will be destined for your box, there are two ways to do that:
Code:
iptables -t nat -I PREROUTING -s 192.168.182.0/24 -p tcp --dport 25 -j DROP
or
Code:
iptables -I FORWARD -s 192.168.182.0/24 -p tcp --dport 25 -j DROP
iptables -I INPUT -s 192.168.182.0/24 -p tcp --dport 25 -j DROP
The first one is more concise, but many people argue against doing filtering in the nat table (hence the filter table).