What are the differences between GNOME and KDE and witch one is better for a newbite? I dunno why both are availble while they don't have almost any differences (of course I could be wrong)! Secondly could anyone tell me how to configure wine correctly?

KDE and GNOME are two very different things. Read for yourself

http://www.kde.org/whatiskde/
http://www.gnome.org/about/

And why are both available? It's all about choice my friend. One of the beauties of Linux/OSS.

both are different but compatible open source GUI environments. GNOME uses GTk while KDE uses Qt (If I am right???). You can read more history on both GUI environments here. As far as configuring wine is concerned, there are zillion posts on this website dealing with wine. Also wine-user-guide is an excellent source.

Good luck!

In regards as to which is better for a newbie, I'd have to say that KDE is better for a total newbie.

Why? More control, more ease of changing things all through a nice GUI. Gnome you can of course change, but the graphics aren't as good, and I've found you do a tad more editing by hand rather than a GUI.

Which should you choose? Whichever you want. I personally prefer Gnome, however am using KDE for the moment mainly because it is easier to use it with SuSE and Gnome doesn't work 100% in SuSE, and also the fact I like the nice graphics (however Gnome can look nice too), but also more control via GUIs. Lots of people who start with KDE end up moving to Gnome, and then eventually to other things such as XFCE or IceWM or Fluxbox.

How do I change my GUI so I can try the other one?

I found that I can switch the by using switchdesk.