Are you trying to boot some Linux OS directly from the flash drive without using the bootloader on the main hard drive? If that's the case, did you select the option to install Lilo to the MBR?
Which Linux are you using on the flash drive?
Is this a Legacy install rather than UEFI?
liloconfig is similar to grub-install with Grub. If you are editing /etc/lilo.conf, you need to run as root user: lilo OR /sbin/lilo or the changes will not be included. Take a look at the links below which give pretty detailed information on installing lilo and modifying it, at the first link you need to scroll down a bit to the section on Lilo:
https://docs.slackware.com/slackbook:booting
The link below explains a Lilo install as performed during an installation of Slackware. As pointed out on the page, you should be able to run it anytime after install by running liloconfig. You need to post the above requested details as you haven't given enough information for detailed instructions.
Also, if you are using or trying to use the usb with UEFI, none of this applies.