This is my first even moderately successful venture with linux, and it still is a pain.
I had a virus ridden HD which I formatted, and then installed Mint distro.
I then shut down, removed the HD and turned my desktop back on. I then receive the Error 15 notification while booting, and don't know how to solve this problem. I've tried sudo update-grub, but I get a notification that the terminal can't find it. Would it be safe to delete anything concerning the GRUB from my primary OS system files?

I'm leery of trying that for obvious reasons..

[QUOTE=Crorse;3924404]This is my first even moderately successful venture with linux, and it still is a pain.

(if you regard this as any form of success-your glass is definately half full).

I had a virus ridden HD which I formatted, and then installed Mint distro.
I then shut down, removed the HD and turned my desktop back on.
(My PC will not work if I remove my HD).

I then receive the Error 15 notification while booting, and don't know how to solve this problem.
(What system are you using, and attempting to repair)?

I've tried sudo update-grub, but I get a notification that the terminal can't find it. Would it be safe to delete anything concerning the GRUB from my primary OS system files? (If you installed to a second HD then removed it-chances are that you have written a new grub on the second drive MBR-refit it and see if it boots)?

I agree with vigi, I am not sure what the following line means?

My first thought is that you have removed the hard-drive, how do you expect to boot into anything?