I'm assuming you're using Ubuntu or a similar distribution.
There is no way to "reset the configuration", but the a better question is what is it you're trying to do?
Do you need DHCP?
Example of a simple interfaces file with dhcp config for eth0:
Code:
# always need the loopback address configured
auto lo
iface lo inet loopback
# dhcp for eth0
auto eth0
iface eth0 inet dhcp
Do you need a different static address?
Example of a simple interfaces file with static address config for eth0:
Code:
# loopback
auto lo
iface lo inet loopback
# eth0 static config
iface eth0 inet static
address 10.51.100.1
netmask 255.255.0.0
gateway 10.51.0.1
(lines beginging with a '#' are comments)