Rebooted as well. Same pop.
Your idea about USB intrigued me because I have a feeling it is a problem with the wireless as well. Not just that the wireless mouse could cause interference, but I think I get a better wireless strength with no USB devices at all plugged in.
I am going to check into the BIOS update. Although it may just be issues addressed in windows with it, perhaps at that level will help with hardware and make some progress in linux. This is an old enough laptop that everything is in the kernel in linux. Should be able to do better than this
update: deleted the link (I had an asound.state) and rebooted to run alsaconf again and on another reboot seems good now. Thank you.