I have a message in my mail:
usb.c: USB device not accepting new address= 14 (error=-110)...: 1 time(s)
usb.c: USB device not accepting new address= 15 (error=-110)...: 1 time(s)
usb.c: USB device not accepting new address= 16 (error=-110)...: 1 time(s)
usb.c: USB device not accepting new address= 17 (error=-110)...: 1 time(s)
usb.c: USB device not accepting new address= 18 (error=-110)...: 1 time(s)
usb.c: USB device not accepting new address= 19 (error=-110)...: 1 time(s)

If i try to restart my mouse with mouseconfig, it just doesn't work
If i kill -9 X process it still doesn't work
i have to restart to get my mouse

Any idea what's wrong with it?

what do you mean, you have to restart to get your mouse?
you restart the system or the xserver?
when you're on console, do you have the mouse working?

try 'cat /dev/mouse' and play with the mouse, you should see some wild characters.. (then CTRL + C to exit)

you can also try changing the info in /etc/X11/XF86Config

do also an LSMOD and tell us what you have ( I mean are you sure kernel sees your mouse?)
be more specific..

This mouse works fine than suddently, it's append... it freezes (micro$oft intellimouse)
the laser just shut down and there is nothing to do, it seems to be a problem with usb ports.

with cat /dev/mouse there is nothing at all.

if i move my mouse in a console, i've get:
catusb_control/bulk_msg: timeout
usb.c:USB device not accepting new address=20 (error 110)
then address=21,22 etc.

in XF86Config, i see two input devices (is this normal?)
Identifier: ................................ "Mouse0".......DevInputMice"
driver: ......................................."mouse"..........."mouse"
Option: ..."Emulate3Buttons"............"yes"................"no"

with lsmod, i sees:
usb-uhci
usbcore
mousedev

I would have to say, move it to another USB port, and then another, until the problem goes away, or Do you know anyone else you can trade mice with (doesn't that sound silly, trade mice...) and see if the problem follows the mouse, or stays with your USB hub ports.

a) enable HOTPLUG (if you have it disabled)
b) try plug in and out while in the console (does it give messages concerning the mouse, or the mouse gets LIGHT on and off?)

c) you do a boot with another mouse (ps/2 better) and then try again with the USB [the whole solution sounds like windowz stuff, but this is the way I managed to work with my INTELLI MOUSE on the hub of my NATURAL PRO keyboard (alos by MS)

how do you enable HOTPLUG?

The behavior you see - I have gotten my setting up an Intellimouse compatible as if it were a generic PS/2 mouse...

This is actually from my Microsoft Intellimouse USB/Wheel - ver 1.4 - optical, just for sanity sake - maybe this will help (maybe not) - FROM XF86Config-4 file:
===
Section "InputDevice"
Identifier "Mouse0"
Driver "mouse"
Option "Device" "/dev/mouse"
Option "Protocol" "IMPS/2"
Option "Emulate3Buttons" "no"
Option "ZAxisMapping" "4 5"
EndSection
===

With USB mouse, the /dev/mouse is actually linked to /dev/input/mice.

I have the same mouse working in a hub of my Natural Pro keyboard and I have these in lsmod:

keybdev 1952 0 (unused)
mousedev 4212 1
hid 18596 0 (unused)
usbmouse 2008 0 (unused)
input 3200 0 [keybdev mousedev hid usbmouse]
uhci 24560 0 (unused)
usbcore 58144 1 [hid usbmouse acm uhci]


take a look here: http://www.linux-usb.org/USB-guide/x194.html