I have one of these:
COOLER MASTER RX-250-U2BN-GP Aluminum / Plastic / Metal 2.5" USB 2.0 X-Craft 250 External Hard drive Enclosure
http://www.newegg.com/Product/Produc...82E16817171020

I can't get it to work on Linux (Suse 9.2 or OpenSuse 10.1)
Is is possible?
Do I have to mount it? (If so, what would be the command?)

Also, why does it have 2 USB plugs?

I can't find it.
When you plug the device into the computer Linux will automatically create an entry in the /dev directory. USB devices show up as SCSI devices, so their names start with the letters sd. Try this. Unplug the device. Wait 30 seconds. Open a terminal window and enter this command.
Then plug the device in, wait a few seconds, and repeat the command. You should see a new device with a name that starts with the letters sd.

You have to mount a partition on the device in order to use it. Search this web site for tags that start with the word mount to find more information about mounting disk partitions.
You should read the user manual. The enclosure has two USB plugs because it gets its power through the USB cables and it draws too much current for one USB plug. Probably. Like I said I couldn't find the product on the New Egg web site.

>>ls /dev/sd*
I did this and there are hundreds of entries.
What action am I to take based on this?

All right. We'll take a different approach. Now that I think of it this is better anyway.

Plug the device into the computer.
Log in as root, open a terminal window, and enter this command.
That will list all of the disks attached to your computer with their partitions.

Now unplug the device. Wait 30 seconds. Enter the same command again. You should notice that one of the disks that was listed in the first instance is not listed in the second instance.

The Suse 9.2 machine is not seeing the drive at all (before & after fdisk is the same, even after reboot)
hmmph...

plug in the device, wait a few seconds, and type:
If the device works ok, it should tell you something about it