I am building a system, and I would like to know if anyone has experience running Linux with the motherboard I have included in the Subject line. Specifically, I will be running Fedora 30.

Thank you.

I looked at the specs. https://www.asus.com/us/Motherboards...pecifications/

The only thing I see that might be problematical is the Nvidia graphics if you want to use Nvidia drivers instead of Nouveau drivers, but my hardware knowledge is hardly encyclopedic.

I had at one time an Asus laptop and it ran Linux like a top, for what it's worth.

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The X299 is only about 4 months newer than the B250 on my newest Asus. I can't remember ever having anything other than OS/2 or Linux on any Asus. My B250 only has openSUSE (TW, 15.0, 15.1), Buster, Bionic, & Tara. It's been solid using up to 3 displays at once with the onboard Intel graphics from a G4600 Kaby Lake HD Graphics 630.

If it's like my older Deluxe Asus motherboards, the BIOS options are seriously extensive, as are the motherboard's features. Figuring them all out should be the only possible trouble to expect.

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I do plan on using two Nvidia video cards. I do not plan on playing games, however; I just want to made use of the CUDA cores as much as possible for processing. Would I need to use the Nvidia driver in this case, or would the Nouveau driver suffice?

Also, speaking of the BIOS, should I expect to have problems upgrading it in the future if I'm running Linux?

Thank you.

There are more than just two "drivers". Which you might need I cannot answer because I have no more knowledge of CUDA than that it exists. FOSS DDX drivers all depend on kernel modesetting (KMS), for which the nouveau kernel driver is required. The competent FOSS "drivers" appropriate to NVidia GPUs number two, nouveau DDX, and modesetting DDX. All my NVidia GPUs are using the nouveau kernel driver and the modesetting DDX for Xorg. Tainting installations here with NVidia drivers is never done here, while the nouveau DDX is used only for occasional testing. Don't be looking for a modesetting package. It is included in the X server package. The nouveau DDX is provided upstream under the name xf86-video-nouveau. Many distros rename their nouveau DDX package, among them Debian and all its derivatives, such as Ubuntu and Linuxmint.

Not at all. You can upgrade BIOS without any installed or live OS, like most current motherboards.

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Okay, thank you both for answering my questions. I will stick with the motherboard, and I feel confident things are going to work.

Thanks.