What about being able to monitor the temperature from various points around the house
& adjust the thermostat accordingly:
http://www.dealextreme.com/details.dx/sku.7003
Or integrate with thermostate & web UI to be able to remotely correct the temp of your house?
Here are some of the things I'm working towards:
Alarm system integration: monitor to tell me if I left the garage door up & web ui to close it.
Phone system integration via asterisk.
As tablets become cheaper, a few discretely installed around the house could become video monitoring stations for cctv security system, intercom/video-intercom etc.
Lighting management: turn on/off outside lights at dusk
Sprinkler system management: Check the local forecast, or integrate with ground moisture levels to automate sprinklers
for most efficient use?