How exactly did you install wine ?
there are many many different ways and they will need different things done to configure wine
the easiest is to use your package manager and install the version that is in the mint16 repos
also there is a very nice QT gui if you need "qt4wine"
also not ALL microsoft "setup.exe" ( i ROYALLY HATE !!!! EVERYTHING IS ALWAYS CALLED SETUP.EXE !!!!!! )
not all will even come close to being able to be used
WHAT is this unknown program
from the screenshot i would guess you did not install wine correctly
open a terminal and post the error from
Code:
cd /to/the/location/of/the/windows/installer
wine setup.exe
and post the output
also in your desktop menu there should be a "wine" entry
and one of then will be " Browse C:\ drive "
and there should be another called "configure wine"