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AFAIK firewire drives are not bootable. You would need something like a boot floppy or boot CD. Any distro would be capable but you would also need to recompile the kernel to include the firewire modules or add them to the initrd.
Where USB is standard on PC these days firewire is not. So you would not be able to plug the drive into any computer. However, if you bought a combo USB / firewire drive then the answer would be yes. Newer computers can boot from a USB device
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