I did a quick google, and turned up this:
http://sites.google.com/site/fedoraonpavilion/
If Fedora will run on it, just about any main line distro should work. There are a few things you should think about first.
This machine is a dual core 64 bit cpu. 64 bit versions are available for most distros. You can run a 32 bit version, if you choose to. The 32 bit versions are a little easier for a noob.
You will need to re-partition your hard drive. I assume you have the 250 Gig drive listed there. The installers have partitioning tools built in. Since I have no I have no idea your experience level, do some reading before you begin. Many distros have nice How-to installs online. So do some googling after you think you know what you want to install.
As for which one to pick, Fedora, Ununtu, Mandriva are all good first time picks. I personally would pick Mandy, it has a very nice installer, good online repos ( that is where all the updates and new so0ftware come from ). You will get lots of opinions on which distro. Pick one.