I downloaded the cedega cvs and got it installed fine but I'm having problems running any program with it. I'm trying to install Ultima On-Line: Age Of Shadows with the UOAOS_July_03.exe demo install from on-line. I googled my problem for a while and found some helpful things on getting error 21 to go away which looks like:

/usr/lib/transgaming_cedega//winex/bin/wine: can't exec 'UOAOS_July_03.exe': error=21

They told me to try and adjust my prelink file in /etc/sysconfig/prelink and setting prelink to no and adding the -no-exec-shield to the PRELINK_OPTS line. I did that and ran /usr/sbin/prelink -ua to apply the changes. After doing so I still get the error, running as root or as my user. If anyone can please help it would be much appreciated.

Also when I run the /usr/sbin/prelink -ua I get this list of errors:

[root@superman Desktop]# /usr/sbin/prelink -ua
/usr/sbin/prelink: /usr/bin/mysqltest: Could not find one of the dependencies
/usr/sbin/prelink: /usr/bin/mysqlbinlog: Could not find one of the dependencies
/usr/sbin/prelink: /usr/bin/mysql: Could not find one of the dependencies
/usr/sbin/prelink: /usr/bin/mysqldump: Could not find one of the dependencies
/usr/sbin/prelink: /usr/bin/mysqlimport: Could not find one of the dependencies
/usr/sbin/prelink: /usr/bin/mysqlshow: Could not find one of the dependencies
/usr/sbin/prelink: /usr/bin/mysqlcheck: Could not find one of the dependencies
/usr/sbin/prelink: /usr/lib/thunderbird-0.9/regchrome: Could not find one of the dependencies
/usr/sbin/prelink: /usr/lib/thunderbird-0.9/thunderbird-bin: Could not find oneof the dependencies
/usr/sbin/prelink: /usr/lib/thunderbird-0.9/TestGtkEmbed: Could not find one ofthe dependencies
/usr/sbin/prelink: /usr/lib/thunderbird-0.9/xpcshell: Could not find one of thedependencies
/usr/sbin/prelink: /usr/lib/transgaming_cedega/winex/bin/wine_relocated: Could not find one of the dependencies
/usr/sbin/prelink: /usr/lib/transgaming_cedega/winex/bin/wine: Could not find one of the dependencies
/usr/sbin/prelink: /usr/lib/transgaming_cedega/winex/bin/wineserver: Could not find one of the dependencies
/usr/sbin/prelink: /usr/lib/firefox-1.0/regchrome: Could not find one of the dependencies
/usr/sbin/prelink: /usr/lib/firefox-1.0/firefox-bin: Could not find one of the dependencies
/usr/sbin/prelink: /usr/lib/firefox-1.0/TestGtkEmbed: Could not find one of thedependencies
/usr/sbin/prelink: /usr/lib/firefox-1.0/xpcshell: Could not find one of the dependencies

Thanks for any help you can give me.

*bump*

Done building font metrics
/home/grimey/.WineCVS/installs/cvscedega/bin/wine: can't exec 'Setup2D.exe': error=21
err:heap:HEAP_GetPtr Invalid heap 00000000!

It's saying that now, anyone know anything about this error 21 stuff? It's extremely annoying, thanks.

See that forum: http://transgaming.org/forum/viewtopic.php?t=1325
it writes everything that you need....
I tried prelink -ua, and it had the same messages, that you had too... and i done all that they wrote on this forum, and now the games work for me, perfectly not the missing dependencies was the problem!!