First I hope this observation (review) ends up in the correct place under Debian, Testing, Squeeze.
Second, this installation is running in VirtualBox as a test.
Third, I'm not a heavy user whatever that is; currently I basically surf the net, use OpenOffice, and a windows program running in Wine.
Why Debian testing? - After looking at DistroWatch and comparing packages with Lenny and unstable sid it seemed like a decent compromise and simple curiosity.

Currently Mint 7 is installed on the wife's desktop, an older Asus AMD motherboard, and Mint 8 on my Acer 3100 laptop (AMD Sempron 3200+ and ATI Radeon Xpress 1100). Both have been fine but prefer Mint 7 over 8; can't put my finger on it but just do. Mint, basically based on Ubuntu with improvements (my opinion), which is based on Debian; but after ready some reviews not sure where they are headed so to speak. What if Ubuntu 10.4 / Mint 9 just doesn't do it for me? So why not just use Debian I ask?

I installed using the "netinst" disk which went fine but took a while to load using either the "check for updates" during install or installing the updates later. We're talking a couple of hours all together and I'm on a 1.5 Mbps DSL line.
I also tried using just the first two CD ISO's which did not work for me; I couldn't get past the stage of loading applications and it never asked for the second CD.
One thing that did throw me a little was using the default "trunk-686" kernel at loading which didn't want to play nice with the VirtualBox Guest Additions. The "2.6.32-3-686" kernel works fine. On a previous install I did remove the "trunk-686" kernel and updated the grub menu, but it wanted to hang after that trying to load the "2.6.32-3-686" kernel. On this install I've left it alone for now.
So far Squeeze has worked fine in VirtualBox for my needs; Web surfing, OpenOffice, Wine (using their latest repository), networking, remote printing, KDE games (wife plays), etc.
Updates have been painless and haven't broken anything yet.
What can I say; it's been pretty uneventful.
I wish I had a machine just to test things without using VirtualBox.
Once Mint 9 comes out I will probably load it on the Desktop and re-install Debian Squeeze on the lappie for real and see how they compare.
In the meantime if something comes up on the current install I'll update.
If you like a Debian base, want the latest software, use a computer to get your work done, so far, Squeeze seems to be a reasonable choice.

"Still Learning"