I tried BlueWhite, and things broke on install (it was a few months ago, and I don't remember exactly what it was). I didn't have much time to be problem-solving, so I tried Slamd64, and the whole installation went smoothly.
The biggest problem I've had is a problem you might have with any 64-bit system: the unconventional location of 64 bit libraries. Slamd64 has a good collection of 64-bit and 32-bit libraries, which really helps, but if you're installing things from source, it's sometimes difficult to tell the compiler to look in /usr/lib64 and not /usr/lib (sometimes it insists on the latter, even if you told it to look in the former). Of course this is not always the case, and it depends on the package.