Welcome to LinuxQuestions.org. That's a very common problem running Office with wine (first, congratulations in getting wine to actually run Office, I could not...). To make it save docs, you've to make sure that you have native version of ole32.dll at wine/system directory. Then add those lines to wine.cfg:
"ole32" = "native"
For more informations about getting windows programs to run under wine, check out Franks Corner:
The best way of getting rid of M$ Windoze is not using Windows programs though, unless really, really necessary. Linux, as for being OpenSource, has a plenty of native alternatives for the majority (for an ordinary user, I'd say for ALL) windows applications available, but free and open source. I'd recommend OpenOffice:
If you are unsure about which Windows program has an equivalent for Linux, there's a cute list in here:
I hope it helps.