I would recommend WineX. You can download the cvs version for free, it is almost the same thing, except it doesn't have InstallShield support.
Then I would have a look at Transgamings website if anyone have CIV III up and running.
Some other links that might be of help with wine stuff:
and if you know German try:
edit: just thought I'd give you the link to CIV III
have fun, don't waste to much time, I have