Apache Config
 

Is it easy/possible to have one apache server listening to two ethernet devices?

I want to split a web traffic load among the two seperately installed eithernet devices. So, traffic for one card should so go to a specific directory and traffic from the other card should go to a completely different set of directories.

Yes, but the configuration is done "per IP", not "per interface". However, the end result is the same. It's pretty self-explanatory if you read through the config file that most dists have (now that you know what to look for!).