Which version are you talking about?
Apache 1.3 and 2.0 do not have large file support build in, 2.1/2.2 do:
I'm not sure if there's a compile option for 1.3/2.0 to include large file support, it's not enabled by default if there is.
This 2 GB limit is an 'old' leftover form linux/unix. Nowadays most 32bit Linux distro's do support files larger then 2GB (large file support).
Hope this helps.