It should find any virus that they have in the difinitions including windoze. I use f-prot just to make sure I don't send a e-mail with one by accident. From what I have read there are very very few Linux viruses out there because the systems are very secure. They are not bullet proof but very secure.
Just like any virus software, keep it updated. I updated mine after the latest virus warning with msblaster.
The windoze viruses should not run on Linux unless you run 'wine' or something that can run the program. If you can run a windoze program in linux you need to be careful that you don't spread it. It should not 'infect' your Linux system though regardless. The biggest concern is spreading it.
You can update your definitions from the command line. There are instructions on the website to do that. I use the command "f-prot /*" to scan. This scans everything and lets you know if there were any infections.
If you burn a virus on the CD, yes it will spread if run or even accessed in some cases on a windoze system. It should not affect Linux but can spread if you send it somehow.
Hope this helps. I'm no expert but you didn't get any other response. Something MAY be better than nothing.