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Errrrrrrr, If talking external flash drive like USB or CF or SD. Read and Write cycles are excessive on full installs which will toast a Flash Drive prematurely. Especially if one lets the default installer loose in Ubuntu and it creates a /swap partition also.
A persistent live USB can boot in any pc that will boot from usb. The "persistent" part provides for updates, adding packages and customizations.
A full install will work only on the machine it is installed on (just like any other hard drive install). It is mated with that hardware with which it is installed.