You leave out a lot of important details, such as what distro etc.
It's a shot in the dark, but, off-hand, it looks like you do not have the kernel headers installed on your machine, so the system is unable to compile the virtual box kernel drivers. Not all distros install by default everything that is needed for compiling software.
Try installing the kernel headers for your kernel using whatever package manager your system uses.
If you need more help, post more information.
Also, please change the subject line to something more descriptive than "Help." You can find the guidelines for posting here: