Yes, many windows games run in linux using wine, but wine can be hard to set up. A special semi-commercial version of wine exists called winex / cedega - www.transgaming.com
- which makes it a lot easier with a nice frontend called point2play. It costs $15, but well worth it. I use it for games in linux, tho I have used free wine in the past with some good results. Winex cedega is better tho.