Does anything look strange? That's not an easy question to answer. It all depends on what's installed on the system, where it's installed, where to store data files, etc.
If you're looking for a suggestion, then I'd continue looking into /usr/share and /usr/lib. Those are the biggest space consumers listed:
du -hs /usr/share/*
du -hs /usr/lib/*
Keep pushing further in until you find the directory that has lots of files you don't recognize or that shouldn't be there.