welcome to LQ!!
First, please stay away from the big, bold, font. I had to turn the volume on my speakers all the way down....
Package manager: Assuming that your Internet connection is working, check to see that at least one repository is enabled. Here is the one I am using:
http://spout.ussg.indiana.edu/linux/...pclinuxos/apt/
In Synaptic: Settings ---> Repositories.
WINE: Is available in the package manager, although it is not the very latest. You have to install WINE first, then install Windows apps.
You might also want to look at Crossover (
http://www.codeweavers.com/). This is the commercial port of WINE.