What is important is not the motherboard but the graphic-board and the monitor.
Look at your hardware specs focusing on the graphic chipset (integrated or on a separate board) its video memory, AGP bus speed and so on.
For the monitor look at max resolution, vertical and horizontal refresh and max colour depth allowed.
Of course you must configure your keyboard and mouse as well.
This link explains how to set up laptops, but I personally found it useful for general purposes as well
Hope this helps