Of course you can do it. For example, I want to mount my new slave hard drive (so it's seen as /dev/hdb1). So first I create a directory as a mount point:
Then you need to know which type of partition, your disk use... and be sure that your running kernel support this type of FS. For example, I use vfat, so I'll type:
mount -t vfat /dev/hdb1 /mnt/data
and that's OK.
Then if you want Linux to do this operation each time it boots, you have to add your mount point into /etc/fstab file