If you have a pen drive you can format it as a boot disk for Fedora. Once you've booted the installer, Fedora also supports installing from ISOs on a hard drive. The Installation Guide has info on both:
As a rule Fedora stays as close to the original software as possible, so for hardware compatibility just search for the names of the hardware on www.google.com/linux.
Note that proprietary drivers from ATI etc. do add performance but may have compatibility and stability issues that the supplied Open Source drivers don't - make sure your system works and do a bit of research before installing any proprietary drivers.