I do not see why you would have a problem. I recently used DSL to test the operation of Linux on my XPS 410 with no problems (short of network drivers). The cores were recognized as two processors and all my RAM and HDD were present. If you have issues, I would recommend DLing a live-CD of the Distro you want to use, if one is available. Ubuntu has an install CD that operates as a LiveCD, so it might be a good option for testing your system.
You will probably need to be a bit more selective with your TV Tuner options. This
applies to Myth TV, but I would imagine that most of these would be compatible with any Linux with some driver work.