I am right now using Fedora Core 6 and 5 as well as Suse 9.1 on Intel 101 GGC board.
I am having no problem. All hardware gets detected properly. Suing internal graphics (( Ati Express200 chipset, 64 MB shared from 1024 MB of RAM ( DDR 400 ))
No problem during installation or in detection of any hardware. If you are using a PCI-Express card, then set the BIOS to PCIExpress , rather than Onboard. Also there is a BIOS release at the intels website ( Bios 313 ) I am using that. Any older version might experience problems with linux.
you can find the BIOS upgrade on the Intel's site.