As mentioned at the beginning, there is cross compatibility through lxrun and ibcs2. Additionally, you can compile software on SCO- assuming you have a development system, which is not usually the case. You can put the GNU development system on SCO OSR5 and Unixware (from Skunkware again), but make files don't often have good support for SCO, and you may find it easier to just get the binaries from Skunkware or an ftp site (see SCO FTP Sites and the FAQ).
from
http://pcunix.com/Linux/scolindiff.html